Phospho-HMG-17 (S29) Polyclonal Antibody, 100µg, (ATB-P0999)

Description

Background:

The protein encoded by this gene binds nucleosomal DNA and is associated with transcriptionally active chromatin. Along with a similar protein, HMGN1, the encoded protein may help maintain an open chromatin configuration around transcribable genes. The protein has also been found to have antimicrobial activity against bacteria, viruses and fungi. [provided by RefSeq, Oct 2014]

Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation (By similarity).

Product datasheet:

References:

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   Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

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