Description

Background:

Transcription factor involved in regulating gene activity following the primary growth factor response. Binds to the DNA sequence 5′-TGA[CG]TCA-3′.

Product datasheet:

Overview

Product Description   Phospho-Jun B (S79) Polyclonal Antibody, 100µg, (ATB-P0159)
Species ReactivitiesHuman,Mouse,Rat
ImmunogenSynthesized peptide derived from human Jun B around the phosphorylation site of S79.

Properties

FormLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions-20°C/1 year
ClonalityPolyclonal

References:

  1. JUNB promotes the survival of Flavopiridol treated human breast cancer cells. Hicks M, et al. Biochem Biophys Res Commun, 2014 Jul 18. PMID 24858691
  2. JunB mediates basal- and TGFβ1-induced smooth muscle cell contractility. Ramachandran A, et al. PLoS One, 2013. PMID 23308222 Free PMC Article
  3. Translational control of JunB, an AP-1 transcription factor, in activated human endothelial cells. Schmid DI, et al. J Cell Biochem, 2013 Jul. PMID 23297064 Free PMC Article
  4. Expression of junB is markedly stimulated by glycyrrhizin in a human hepatoma cell line. Koike K. Oncol Rep, 2011 Mar. PMID 21225234
  5. Over-expression of JunB inhibits mitochondrial stress and cytotoxicity in human lymphoma cells exposed to chronic oxidative stress. Son YO, et al. BMB Rep, 2010 Jan. PMID 20132737
  6. jun-B inhibits and c-fos stimulates the transforming and trans-activating activities of c-jun.
    Schuette J., Viallet J., Nau M., Segal S., Fedorko J., Minna J.
    Cell 59:987-997(1989) [PubMed] [Europe PMC] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  7. Isolation of human cDNA clones of jun-related genes, jun-B and jun-D.
    Nomura N., Ide M., Sasamoto S., Matsui M., Date T., Ishizaki R.
    Nucleic Acids Res. 18:3047-3048(1990) [PubMed] [Europe PMC] Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  8. Complex genetic organization of junB: multiple blocks of flanking evolutionarily conserved sequence at the murine and human junB loci.
    Phinney D.G., Tseng S.W., Ryder K.
    Genomics 28:228-234(1995) [PubMed] [Europe PMC] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Tissue: Placenta.
  9. NIEHS SNPs program
    Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databasesCited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], VARIANT VAL-230.
  10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Pancreas.
external
sizechest(in.)waist(in.)hips(in.)
XS34-3627-2934.5-36.5
S36-3829-3136.5-38.5
M38-4031-3338.5-40.5
L40-4233-3640.5-43.5
XL42-4536-4043.5-47.5
XXL45-4840-4447.5-51.5

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