Phospho-Ras-GRF1 (S916) Polyclonal Antibody, 100µg, (ATB-P0975)
$238.00
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Description
Background:
Promotes the exchange of Ras-bound GDP by GTP.
Product datasheet:
Overview | |
| Product Description | Phospho-Ras-GRF1 (S916) Polyclonal Antibody, 100µg, (ATB-P0975) |
| Species Reactivities | Mouse,Rat |
| Immunogen | Synthesized peptide derived from human Ras-GRF1 around the phosphorylation site of S916. |
Properties | |
| Form | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Storage Instructions | -20°C/1 year |
| Clonality | Polyclonal |
References:
- Age-dependent role for Ras-GRF1 in the late stages of adult neurogenesis in the dentate gyrus. Darcy MJ, et al. Hippocampus, 2014 Mar. PMID 24174283 Free PMC Article
- Mice Lacking Ras-GRF1 Show Contextual Fear Conditioning but not Spatial Memory Impairments: Convergent Evidence from Two Independently Generated Mouse Mutant Lines. d’Isa R, et al. Front Behav Neurosci, 2011. PMID 22164138 Free PMC Article
- Novel RasGRF1-derived Tat-fused peptides inhibiting Ras-dependent proliferation and migration in mouse and human cancer cells. Sacco E, et al. Biotechnol Adv, 2012 Jan-Feb. PMID 21620943
- RasGrf1 deficiency delays aging in mice. Borrás C, et al. Aging (Albany NY), 2011 Mar. PMID 21422498 Free PMC Article
- Imprinted Rasgrf1 expression in neonatal mice affects olfactory learning and memory. Drake NM, et al. Genes Brain Behav, 2011 Jun. PMID 21251221 Free PMC Article
- Isolation of multiple mouse cDNAs with coding homology to Saccharomyces cerevisiae CDC25: identification of a region related to Bcr, Vav, Dbl and CDC24.
Cen H., Lowy D.D.
EMBO J. 11:4007-4015(1992) [PubMed] [Europe PMC] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: BALB/c. - Cloning by functional complementation of a mouse cDNA encoding a homologue of CDC25, a Saccharomyces cerevisiae RAS activator.
Martegani E., Vanoni M., Zippel R., Coccetti P., Brambilla R., Ferrari C., Sturani E.P., Alberghina L.
EMBO J. 11:2151-2157(1992) [PubMed] [Europe PMC] Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 791-1262. Strain: Swiss.
Tissue: Brain. - Identification of a mammalian gene structurally and functionally related to the CDC25 gene of Saccharomyces cerevisiae.
Wei W., Mosteller R.D., Sanyal P., Gonzales E., McKinney D., Dasgupta C., Li P., Liu B.-X., Broek D.
Proc. Natl. Acad. Sci. U.S.A. 89:7100-7104(1992) [PubMed] [Europe PMC] Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1031-1226. - Ras-specific exchange factor GRF: oligomerization through its Dbl homology domain and calcium-dependent activation of Raf.
Anborgh P.H., Qian X., Papageorge A.G., Vass W.C., DeClue J.E., Lowy D.R.
Mol. Cell. Biol. 19:4611-4622(1999) [PubMed] [Europe PMC] Cited for: FUNCTION, OLIGOMERIZATION, INTERACTION WITH RASGRF2, MUTAGENESIS OF LEU-263 AND 394-LEU–LEU-400. - Cloning and characterization of mouse UBPy, a deubiquitinating enzyme that interacts with the ras guanine nucleotide exchange factor CDC25(Mm)/Ras-GRF1.
Gnesutta N., Ceriani M., Innocenti M., Mauri I., Zippel R., Sturani E., Borgonovo B., Berruti G., Martegani E.
J. Biol. Chem. 276:39448-39454(2001) [PubMed] [Europe PMC] Cited for: UBIQUITINATION, INTERACTION WITH USP8.
| size | chest(in.) | waist(in.) | hips(in.) |
|---|---|---|---|
| XS | 34-36 | 27-29 | 34.5-36.5 |
| S | 36-38 | 29-31 | 36.5-38.5 |
| M | 38-40 | 31-33 | 38.5-40.5 |
| L | 40-42 | 33-36 | 40.5-43.5 |
| XL | 42-45 | 36-40 | 43.5-47.5 |
| XXL | 45-48 | 40-44 | 47.5-51.5 |
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