Phospho-Casein Kinase Iγ1/2/3 (Y263) Polyclonal Antibody, 100µg, (ATB-P1040)

Description

Background:

This gene encodes a member of the casein kinase I gene family. The encoded protein is a serine/threonine kinase that phosphorylates acidic proteins, and participates in pathways for cell growth. [provided by RefSeq, Nov 2011]

Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Regulates fast synaptic transmission mediated by glutamate (By similarity). Phosphorylates CLSPN.

Product datasheet:

References:

1. Molecular cloning, mapping and characterization of a human CK1gamma1 gene. Guo L, et al. Int J Mol Med, 2002 Aug. PMID 12119564
2. Cloning, expression analysis and chromosome mapping of human casein kinase 1 gamma1 (CSNK1G1): identification of two types of cDNA encoding the kinase protein associated with heterologous carboxy-terminal sequences. Kusuda J, et al. Cytogenet Cell Genet, 2000. PMID 11124537
3. Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion. Rena G, et al. EMBO J, 2002 May 1. PMID 11980723 Free PMC Article
4. Casein kinase 1γ1 inhibits the RIG-I/TLR signaling pathway through phosphorylating p65 and promoting its degradation. Wang Y, et al. J Immunol, 2014 Feb 15. PMID 24442433
5. Cyclin T1-dependent genes in activated CD4 T and macrophage cell lines appear enriched in HIV-1 co-factors. Yu W, et al. PLoS One, 2008 Sep 5. PMID 18773076 Free PMC Article
6. Cloning, expression analysis and chromosome mapping of human casein kinase 1 gamma1 (CSNK1G1): identification of two types of cDNA encoding the kinase protein associated with heterologous carboxy-terminal sequences.
   Kusuda J., Hirai M., Tanuma R., Hashimoto K.
   Cytogenet. Cell Genet. 90:298-302(2000) [PubMed] [Europe PMC] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1L AND 1S).
7. The full-ORF clone resource of the German cDNA consortium.
   Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I.
   BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Brain.
8. Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R.
   , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C.
   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases

   Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
   The MGC Project Team
   Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1L). Tissue: Muscle.
10. An unappreciated role for RNA surveillance.
    Hillman R.T., Green R.E., Brenner S.E.
    Genome Biol. 5:R8.1-R8.16(2004) [PubMed] [Europe PMC] Cited for: SPLICE ISOFORM(S) THAT ARE POTENTIAL NMD TARGET(S).