Phospho-Stat6 (T645) Polyclonal Antibody, 100 µg, (ATB-P0255)

Description

Background:

Carries out a dual function: signal transduction and activation of transcription. Involved in IL4/interleukin-4- and IL3/interleukin-3-mediated signaling.

Product datasheet:

References:

1. An interleukin-4-induced transcription factor: IL-4 Stat.
   Hou J., Schindler U., Henzel W.J., Ho T., Brasseur M., McKnight S.L.
   Science 265:1701-1706(1994) [PubMed] [Europe PMC] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
2. Localization of the human stat6 gene to chromosome 12q13.3-q14.1, a region implicated in multiple solid tumors.
   Patel B.K., Keck C.L., O’Leary R.S., Popescu N.C., LaRochelle W.J.
   Genomics 52:192-200(1998) [PubMed] [Europe PMC] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
3. STAT6 mRNA, nirs splice variant 2.
   Tabata Y., Sameshima E., Hayashi A., Iida K., Mitsuyama M., Kanai S., Furuya T., Saito T.
   Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databasesCited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2).
4. Complete sequencing and characterization of 21,243 full-length human cDNAs.
   Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
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   Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC]

   Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3). Tissue: Tongue.

5. SeattleSNPs variation discovery resource
   Submitted (OCT-2001) to the EMBL/GenBank/DDBJ databasesCited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], VARIANT ARG-181.
6. The finished DNA sequence of human chromosome 12.
   Scherer S.E., Muzny D.M., Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.
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   Nature 440:346-351(2006) [PubMed] [Europe PMC]

   Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
   The MGC Project Team
   Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1). Tissue: Uterus.
8. An LXXLL motif in the transactivation domain of STAT6 mediates recruitment of NCoA-1/SRC-1.
   Litterst C.M., Pfitzner E.
   J. Biol. Chem. 277:36052-36060(2002) [PubMed] [Europe PMC] Cited for: INTERACTION WITH NCOA1, MUTAGENESIS OF LEU-802 AND LEU-805.
9. T-cell protein tyrosine phosphatase, distinctively expressed in activated-B-cell-like diffuse large B-cell lymphomas, is the nuclear phosphatase of STAT6.
   Lu X., Chen J., Sasmono R.T., Hsi E.D., Sarosiek K.A., Tiganis T., Lossos I.S.
   Mol. Cell. Biol. 27:2166-2179(2007) [PubMed] [Europe PMC] Cited for: FUNCTION IN IL4 SIGNALING, PHOSPHORYLATION, DEPHOSPHORYLATION BY PTPN2.
10. Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.
    Bienvenut W.V., Sumpton D., Martinez A., Lilla S., Espagne C., Meinnel T., Giglione C.
    Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS].